The answer to this question is whatever time of day you’ll best remember to take it, says Sharon T. Phelan, MD. For some women, that might be in the morning. For others, it might be at bedtime, right after brushing your teeth. There’s no one time of day that’s better for absorption or anything like that, so that’s not something to be concerned about.
But if your prenatal vitamin consistently makes you feel nauseous, you should try taking it during a meal. If that doesn’t help, talk to your doctor about other options. Some women are able to substitute two over-the-counter chewable children’s vitamins in place of the big prenatal pill (just check with the doc first before making the switch).