What Is Estradiol?

What is estradiol, and how does it affect conception?
ByJohn Rinehart, MD, PhD, Reproductive Medicine Institute, Chicago
Fertility Specialist
March 2, 2017
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Estradiol is a type of estrogen, the female hormone that’s responsible for the development of the uterus, fallopian tubes and your other important baby-making bits. It’s considered the most important form of estrogen, and most if it is made and released from the ovaries and adrenal cortex.

Your doctor may perform an estradiol test to determine how much of the hormone you have floating around in your body. Estradiol levels vary during your menstrual cycle and peak at ovulation. If you’re undergoing IVF, you’ll be given the test to determine if you’re ready for treatment. Levels are also often checked once you’re starting treatment as a way to measure the growth of eggs and determine whether you’re on track. Estradiol is also sometimes given in a synthetic form as a treatment for menopause, since it eases symptoms like hot flashes and vaginal dryness and boosts bone health.
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