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Dr. Joseph Hill

Q&A: Should I Consider Intrauterine Insemination?

When should I think about IUI? How much success does it have in treating infertility? And should I combine it with Clomid?

A very good study published by the New England Journal of Medicine in 1999 showed that for women with otherwise unexplained infertility, IUI (intrauterine insemination) alone allowed only an 8% increase in pregnancy rates over three cycle attempts. In non-ovulating women who combine  Clomid with IUI, the chance of pregnancy is between 10 and 20%, depending on age. When ovulation induction through gonadotropin injections is combined with IUI, the chance of pregnancy is approximately 12 to 17%, depending on age. These percentages are based on a background chance success for women with unexplained infertility undergoing no therapy of only 4%.